The Small Molecule Screening Facility (SMSF) fosters collaborative drug discovery research between chemists, biologists and physician scientists that leads to the identification of new small molecules that inhibit disease targets and phenotypes in biochemical and cellular models relevant to any therapeutic area.
To learn more about our services and discuss your needs, contact Gene Ananiev (geananiev@wisc.edu). Free estimates provided.
More about SMSF
Contact Us
Faculty Leader: Tim Bugni
Facility Manager: Gene Ananiev, geananiev@wisc.edu, 608-265-8687
Computational Modeling and Virtual Screening:
Ken Satyshur, satyshur@wisc.edu
Spencer Ericksen, ssericksen@wisc.edu
Room 6003 WIMR
Services Offered
High-Throughput Screening
Assay Ready Plates
Seahorse Metabolism Analysis
Mycoplasma Detection
Molecular Modeling and Virtual Screening
Equipment and Pricing
The Small Molecule Screening Facility (SMSF) has specialized equipment dedicated to drug discovery. Scientists from UW-Madison, other universities or private companies may receive training on some pieces of the shared equipment
Acknowledgments
Funding received from the UWCCC Cancer Center Support Grant (CCSG) for published research, including the use of UWCCC Shared Resources to generate or analyze data, or conduct clinical trials, needs to reference the UWCCC. See Acknowledging UWCCC in Publications, Posters, and Presentations.
View the UW Research Expertise website for more information on other UW–Madison laboratory facilities that provide state-of-the-art instrumentation and expert scientific staff.
SMSF's Latest Publications
- Practical Model Selection for Prospective Virtual Screening
- Biemamides A-E, Inhibitors of the TGF-β Pathway That Block the Epithelial to Mesenchymal Transition
- Thalassosamide, a Siderophore Discovered from the Marine-Derived Bacterium Thalassospira profundimaris
- Machine Learning Consensus Scoring Improves Performance Across Targets in Structure-Based Virtual Screening
- A High-Throughput Screening Strategy to Identify Inhibitors of SSB Protein-Protein Interactions in an Academic Screening Facility
SMSF's Latest Posts
Rigor and Reproducibility Via Virtual Screening in SMSF
On the computational side of SMSF, we have made big strides in rigor and reproducibility with computational procedures. This reflects a broader shift in this direction by the computational chemistry community at-large. Our main services …
March 11, 2020Employee Spotlight: Gene Ananiev, Instrumentation Tech
Learn more about Gene Ananiev, a third generation scientist and Facility Manager in the Small Molecule Screening Facility.
September 12, 2019New DDC Faculty Leader: Dr. Tim Bugni
We are happy to announce Dr. Tim Bugni, PhD as the new Faculty Leader for the Drug Development Core (DDC). Dr. Bugni is a Professor in the School of Pharmacy’s Pharmaceutical Sciences Division and he …
May 30, 2019- More DDC posts
- More SMSF posts