The Small Molecule Screening Facility (SMSF) fosters collaborative drug discovery research between chemists, biologists and physician scientists that leads to the identification of new small molecules that inhibit disease targets and phenotypes in biochemical and cellular models relevant to any therapeutic area.
To learn more about our services and discuss your needs, contact Michael Hoffmann (fmhoffma@wisc.edu) or Gene Ananiev (geananiev@wisc.edu). Free estimates provided.
More about SMSF
Contact Us
Faculty Leader: Michael Hoffmann, fmhoffma@wisc.edu, 608-263-2890
Facility Manager: Gene Ananiev, geananiev@wisc.edu, 608-265-8687
Computational Modeling and Virtual Screening:
Scott Wildman, swildman@wisc.edu
Ken Satyshur, satyshur@wisc.edu
Spencer Ericksen, ssericksen@wisc.edu
Room 6003 WIMR
Services Offered
High-Throughput Screening
Assay Ready Plates
Seahorse Metabolism Analysis
Mycoplasma Detection
Molecular Modeling and Virtual Screening
Equipment and Pricing
The Small Molecule Screening Facility (SMSF) has specialized equipment dedicated to drug discovery. Scientists from UW-Madison, other universities or private companies may receive training on some pieces of the shared equipment
Acknowledgments
Funding received from the UWCCC Cancer Center Support Grant (CCSG) for published research, including the use of UWCCC Shared Resources to generate or analyze data, or conduct clinical trials, needs to reference the UWCCC. See Acknowledging UWCCC in Publications, Posters, and Presentations.
View the UW Research Expertise website for more information on other UW–Madison laboratory facilities that provide state-of-the-art instrumentation and expert scientific staff.
SMSF's Latest Publications
- Practical Model Selection for Prospective Virtual Screening
- Biemamides A-E, Inhibitors of the TGF-β Pathway That Block the Epithelial to Mesenchymal Transition
- Thalassosamide, a Siderophore Discovered from the Marine-Derived Bacterium Thalassospira profundimaris
- Machine Learning Consensus Scoring Improves Performance Across Targets in Structure-Based Virtual Screening
- A High-Throughput Screening Strategy to Identify Inhibitors of SSB Protein-Protein Interactions in an Academic Screening Facility
SMSF's Latest Posts
Core Spotlight: Small Molecule Screening Facility
Find new drugs with high throughput screening and computational expertise Are you interested in finding new drugs to cure cancer or solve the antibiotic crisis? Well, the Small Molecule Screening Facility (SMSF) can’t promise such broad …
December 4, 2018Forgotten Molecules
On a rainy day last fall, chemist Scott Wildman left his office on the UW– Madison campus and drove to a retirement community on the city’s west side to bring 40 years of scientific work out of …
May 14, 2018Machine Learning in Drug Discovery
August 28, 2017- More DDC posts
- More SMSF posts