The Small Molecule Screening Facility (SMSF) just received word that a manuscript submitted to Biometrics was accepted. This work emerges from a collaborative project with graduate student Peng Yu (lead author) from Prof. Michael A. …
SMSF
Rigor and Reproducibility Via Virtual Screening in SMSF
On the computational side of SMSF, we have made big strides in rigor and reproducibility with computational procedures. This reflects a broader shift in this direction by the computational chemistry community at-large. Our main services …
Employee Spotlight: Gene Ananiev, Instrumentation Tech
Learn more about Gene Ananiev, a third generation scientist and Facility Manager in the Small Molecule Screening Facility.
New DDC Faculty Leader: Dr. Tim Bugni
We are happy to announce Dr. Tim Bugni, PhD as the new Faculty Leader for the Drug Development Core (DDC). Dr. Bugni is a Professor in the School of Pharmacy’s Pharmaceutical Sciences Division and he …
Novel Library of Screening Compounds to Catalyze Drug Discovery
The UW Carbone Cancer Center’s Drug Development Core (DDC) Medicinal Chemistry Center has recently developed a structurally novel library of screening compounds as part of a UW2020 grant spearheaded by Prof. Jennifer Golden and Prof. …
Core Spotlight: Small Molecule Screening Facility
Find new drugs with high throughput screening and computational expertise Are you interested in finding new drugs to cure cancer or solve the antibiotic crisis? Well, the Small Molecule Screening Facility (SMSF) can’t promise such broad …
Forgotten Molecules
On a rainy day last fall, chemist Scott Wildman left his office on the UW– Madison campus and drove to a retirement community on the city’s west side to bring 40 years of scientific work out of …
Machine Learning in Drug Discovery
SMSF Provides Assay Ready Plates
Tip-less acoustic liquid handling using the Labcyte ECHO can transfer as little as 2.5nL of DMSO compound solution between plates. This capability allows us to offer assay ready plates for screening at low cost. The …
New SMSF Screening Library
The SMSF now has a 100,000 compound library from Life Chemicals ready for screening. The recent addition of our fourth subset of 25,000 compounds complements the previous sets (added 1/2009, 10/2009 and 9/2015). These sets …