The Small Molecule Screening Facility (SMSF) just received word that a manuscript submitted to Biometrics was accepted. This work emerges from a collaborative project with graduate student Peng Yu (lead author) from Prof. Michael A. …
DDC
Rigor and Reproducibility Via Virtual Screening in SMSF
On the computational side of SMSF, we have made big strides in rigor and reproducibility with computational procedures. This reflects a broader shift in this direction by the computational chemistry community at-large. Our main services …
New DDC Faculty Leader: Dr. Tim Bugni
We are happy to announce Dr. Tim Bugni, PhD as the new Faculty Leader for the Drug Development Core (DDC). Dr. Bugni is a Professor in the School of Pharmacy’s Pharmaceutical Sciences Division and he …
New UW iLab Site
We are happy to announce the new UW iLab Core Facility Management website! The iLab core management application is a web-based solution designed to streamline core facility management through assisting managers with their billing, invoicing, reservation …
Novel Library of Screening Compounds to Catalyze Drug Discovery
The UW Carbone Cancer Center’s Drug Development Core (DDC) Medicinal Chemistry Center has recently developed a structurally novel library of screening compounds as part of a UW2020 grant spearheaded by Prof. Jennifer Golden and Prof. …
MicroScale Thermophoresis (MST) to Quantify Molecular Interactions
Are you interested in measuring the binding affinity of your target biomolecule to another molecule? If so, you may want to try using MicroScale Thermophoresis (MST) to quantify your molecular interactions! As part of a …
New Equipment: Shimadzu HPLC for PK/PD
The Cancer Pharmacology Lab (CPL) recently acquired a new Shimadzu high performance liquid chromatography (HPLC) instrument, boosting their capacity to run pharmacokinetic/pharmacodynamic analyses! The new instrument features an SPD-M20A Diode Array Detector module, allowing it …
Core Spotlight: Small Molecule Screening Facility
Find new drugs with high throughput screening and computational expertise Are you interested in finding new drugs to cure cancer or solve the antibiotic crisis? Well, the Small Molecule Screening Facility (SMSF) can’t promise such broad …
Forgotten Molecules
On a rainy day last fall, chemist Scott Wildman left his office on the UW– Madison campus and drove to a retirement community on the city’s west side to bring 40 years of scientific work out of …