The UWCCC Clinical Research Imaging Core (CRIC) partners closely with the UW Radiology Department’s Radius Image Analysis Core Lab and Medical Imaging Research Support (MIRS) to provide imaging support related to cancer research. This partnership contributes to the effective and efficient use of image-based outcome measures in research performed at the UW Carbone Cancer Center.
Developments and Resources
UW SMPH Department of Radiology Radius Rebrand
To provide imaging services to the University of Wisconsin Carbone Cancer Center clinical trials, CRIC partnered with the image analysis group within the UW Department of Radiology Medical Imaging Research Support (MIRS). The image analysis group, previously known as MIRS-Image Analysis or MIRS-IA, has re-branded itself and is now Radius.
The Radius re-brand will not affect any operations within cancer center clinical trials.
CRIC is excited to continue its relationship with Radius to provide tumor response assessments and scan de-identification and submission services to UWCCC Clinical trials. CRIC looks forward to continuing its prosperous partnership with Radius and further expanding our service lines.
CRIC News
iwCLL Tumor Response Criteria Piloted for Lymphoma Clinical Trials
The Clinical Research Imaging Core (CRIC) and the Radius Lab are piloting a potential new service line for lymphoma clinical trial tumor response assessments using iwCLL Assessment Criteria. The iwCLL assessment criteria is unique in …
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Faculty Leader
Steve Cho, MD
CRIC Manager
Annelise Van Keulen, BS RT(R)(MR)ARRT
UW Imaging Modality Hardware
Services
Integration with Clinical Research at UW:
CRIC provides the highest quality of imaging expertise and management to cancer center studies, with close interaction with the UWCCC DOTs and other investigators. These services range from protocol inception and imaging manual development to scan submission for central review and image analysis.
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CRIC and the UWCCC DOTS
CRIC serves as the UWCCC entry point into UW Radiology MIRS for imaging expertise and review for clinical trials run through the UWCCC Disease Oriented Teams (DOTs). CRIC provides imaging manual development and management to DOTs to ensure scan parameters are appropriate, accessible to imaging technologists, and to streamline the patient’s experience as much as possible.
Protocol Planning and Regulatory Management
- Protocol feasibility review for imaging components with input from modality experts as needed (ex. CT, MRI, PET, etc.)
- Imaging manual development for clinical protocols
- Regulatory management and oversight (Appendix M DHS, IND, RDRC, HRUC)
- Scheduling PET radiopharmaceutical production and scans
Scan Submission for Central Review
- Scan de-identification and submission to central review for sponsored and cooperative group studies is performed by CRIC and Radius staff
- Imaging query management
Radius
- Radius is the image analysis core lab within MIRS that CRIC partners with to provide tumor imaging response assessments, providing dedicated imaging excellence to UWCCC clinical trials
- Tumor response assessments are closely integrated with UW Radiology clinical workflows to ensure rapid turn-around time and consistent reporting
- Response assessments done use widely used validated criteria, including RECIST v 1.1, irRECIST, iRECIST, imRECIST, LYRIC, and Lugano
Clinical Imaging Research Resources
Acknowledging CRIC
Any published research which received funding from the UWCCC Cancer Center Support Grant (CCSG), including the use of UWCCC Shared Resources to generate or analyze data or conduct clinical trials, must acknowledge the UWCCC. See Acknowledging UWCCC in Publications, Posters, and Presentations. Please acknowledge “UWCCC Clinical Research Imaging Core” for any work supported by CRIC. Thank you!
Sample Acknowledgment
“The author(s) thank the University of Wisconsin Carbone Cancer Center Clinical Research Imaging Core, supported by P30 CA014520, for use of its services.”