Research co-led by UW Carbone members Drs. Amy Trentham-Dietz and Oguzhan Alagoz has received a five-year, $8.7 million grant from the National Cancer Institute to use computational modeling to guide clinical translation of breast cancer screening and treatment strategies.
Trentham-Dietz and Alagoz co-lead the Cancer Intervention and Surveillance Modeling Network (CISNET) Breast Working Group, which also includes UW Carbone researchers Drs. Ronald Gangnon and Christoph Lee. CISNET BWG collaborators include Stanford University, the University of Texas MD Anderson Cancer Center, Georgetown University, and Dana-Farber Cancer Institute.
The researchers will use this funding to model the impact of different risk-reduction and new targeted treatment strategies on a range of specific patient groups. They’ll also examine the potential benefits of artificial intelligence tools to read screening mammograms and the impact of post-diagnosis behavioral interventions on survival outcomes.
Trentham-Dietz is the Associate Director for Population Sciences at UW Carbone. Alagoz is the only engineer on the grant and will be leading the work related to artificial intelligence tools applied to breast cancer screening. AI-based mammography interpretation technologies are being developed rapidly and are expected to play an increasingly important role in breast cancer screening and breast imaging.