Services currently provided by the Genome Editing and Animal Models Shared Resource include:
- CRISPR/Cas9 design, consultation, and synthesis for mice, rats, and cell lines
- Generation of transgenic mice and rats by pronuclear microinjection
- Generation of mouse models from embryonic stem (ES) cells
- Cryopreservation of mouse and rat embryos and sperm
- Rederivation of rodent model strains
- Other molecular biology and animal services related to transgenic and genome editing technology
We carefully discuss investigator needs to ensure the customized projects are ideally suited for the investigator’s needs. We have extensive expertise developing CRISPR/Cas9, generating new CRISPR/Cas9 models, and embryo manipulation of many mouse and rat strains.
Learn more about the Genome Editing Facility and Animal Models Facility.
Acknowledgments
Any published research which received funding from the UWCCC Cancer Center Support Grant (CCSG), including the use of UWCCC Shared Resources to generate or analyze data or conduct clinical trials, must reference the UWCCC. See Acknowledging UWCCC in Publications, Posters and Presentations. Please acknowledge “UWCCC Genome Editing and Animal Models Shared Resource” for any work supported by GEAM. Thank you!
Sample Acknowledgment
“The author(s) thank the University of Wisconsin Carbone Cancer Center Genome Editing and Animal Models Shared Resource, supported by P30 CA014520, for use of its facilities and services.”