Cancer Pharmacology Lab

What We Do


Cancer Pharmacology Lab services include:

  • Sample Acquisition
  • Pharmacokinetic Analytical Assays
  • Pharmacodynamic Assays
  • Preclinical Analytic Services
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Our instrumentation allows us to analyze a variety of matrices, including human and animal blood, plasma, serum, urine, breast and brain tissue.
We have validated HPLC and LC/MS assays for a variety of compounds, including including capecitabine, erlotinib, exemestane, paclitaxel, POMx, polyamines, phenylephrine, sorafenib, talazoparib, UAB30, and other compounds. We also offer method development services for the analysis of novel compounds.

Pharmacokinetics Example
Shown above is a chromatogram with diode array detector measurements of capecitabine metabolites (5’-Fluorouracil, 5’-Deoxy-5’Fluorocytidine, and 5’-Deoxy-5’Fluorouridine)

We offer a variety of pharmacodynamics analysis services, in coordination with other cores as needed.

Sample Acquisition Service
We support protocol-specific collection, processing, storage and shipping of biospecimens for clinical trials


Funding received from the UWCCC Cancer Center Support Grant (CCSG) for published research, including the use of UWCCC Shared Resources to generate or analyze data, or conduct clinical trials, needs to reference the UWCCC. See Acknowledging UWCCC in Publications, Posters, and Presentations. Please acknowledge “UWCCC Cancer Pharmacology Laboratory” for any work supported by the CPL.  Thank you!

Sample Acknowledgment

“The author(s) thank the University of Wisconsin Carbone Cancer Center Cancer Pharmacology Laboratory, supported by P30 CA014520, for use of its facilities and services.”