Circulating Biomarker Core

The Circulating Biomarker Core (CBC) provides development and translation of circulating biomarker assays for basic science research, clinical trials and clinical-grade assays. The CBC operates within the UW Carbone Cancer Center and is affiliated with the CLIA/CAP-accredited facility at the Wisconsin State Lab of Hygiene. The CBC performs a broad range of liquid biopsy assays, including cell free DNA, immune cell studies and multi-plexed analyses of circulating tumor cells. Active collaborations with UW Engineering and private companies have made cutting edge technologies available for users, depending on research interests. One of these technologies (Salus Discovery, LLC) is currently in use for several multi-institutional clinical trials including cooperative group trials.

CBC Workflow
CBC logo

Staff

Facility Manager: Jennifer Schehr PhD

Faculty Leaders

Marina Sharifi

Credentials: MD, PhD

Position title: Co-Director, Circulating Biomarker Core | Assistant Professor Department of Medicine Division of Hematology/Oncology

Email: msharifi@wisc.edu

Joshua M. Lang

Credentials: MD, MS

Position title: Director, Circulating Biomarker Core | Associate Professor Department of Medicine Division of Hematology/Oncology

Email: jmlang@medicine.wisc.edu

Shuang (George) Zhao

Credentials: MD, MSE

Position title: Co-Director and Lead Bioinformatician, Circulating Biomarker Core | Assistant Professor Department of Human Oncology

Email: shgzhao@humonc.wisc.edu

Contact Us

For questions about utilizing the CBC for clinical specimens and trials, or to inquire about laboratory/computational positions and training opportunities, please email cbc@uwcarbone.wisc.edu.

Location

K4/517 CSC

 

Acknowledging CBC

Any published research which received funding from the UWCCC Cancer Center Support Grant (CCSG), including the use of UWCCC Shared Resources to generate or analyze data or conduct clinical trials, must acknowledge the UWCCC. See Acknowledging UWCCC in Publications, Posters, and Presentations. Please acknowledge “UWCCC Circulating Biomarker Core” for any work supported by the CBC.  Thank you!

Sample Acknowledgment

“The author(s) thank the University of Wisconsin Carbone Cancer Center Circulating Biomarker Core, supported by P30 CA014520, for use of its facilities and services.”