Integrated Pathology and Radiology Core

Leadership

Garrett_John-headshot

John Garrett, PhD
Core Co-Director

Professor (CHS), Radiology

Wei Huang, MD
Core Co-Director

Professor (CHS), Pathology

Core Summary

The Integrated Pathology Radiology Core (iPRC) of the UW Prostate Cancer SPORE is dedicated to providing expert and reliable pathology and imaging services to enhance translational prostate cancer (PC) research.

The theme of this core is to provide our UW Prostate Cancer SPORE investigators with a wide range of integrated and coordinated pathology and radiology services including high quality and extensively annotated biospecimens, state-of-the-art pathology, and advanced radiology imaging. The iPRC will provide services and infrastructure to allow for reliable, reproducible, and high-quality pathology data to be linked with radiologic imaging tumor identification and lesion-to-lesion correlation.

The mission of the iPRC is to provide the type and quality of services that will enable Prostate Cancer SPORE investigators to address pathology, radiology, and quantitative imaging translational aims as well as generate reliable and clinically significant findings that will impact treatment outcomes.

iPRC Core Aims

Aim 1 – Collect, process, preserve, annotate, and distribute quality biospecimens and provide a full range of expert pathology consultation and services to the SPORE investigators.

Aim 2 – Build a digital whole slide image (WSI) database with detailed histological and clinical annotations for pathology-radiology correlation studies for SPORE investigators and future collaboration projects.

Aim 3 – Provide advanced radiology imaging services, integrated with pathology, to enable translational correlation and analyses.

Aim 4 – Build a co-registered pathology-radiology image repository to serve and support UW Prostate Cancer SPORE investigators, and the wider PC research community.