The mission of the UWCCC Translational Science BioCore (TSB) is to facilitate research by providing comprehensive services that enable cellular and molecular characterization of animal models and human derived biospecimens with deidentified clinical data. These services are provided through the combined expertise and equipment of the BioBank, the Translational Research Initiatives in Pathology (TRIP) laboratory, and the Experimental Animal Pathology Laboratory (EAPL).
The TSB focuses on support to researchers in the following three critical areas:
- Collection and distribution of patient-consented human-derived biospecimens with clinical data
- Construction and distribution of disease-specific human tissue microarrays (TMAs), fully annotated with relevant clinical data
- High quality services, expertise, and infrastructure in cellular, molecular, quantitative, and computational pathology
Faculty Leaders
Kristina Matkowskyj – TSB Faculty Director, TRIP Co-Faculty Leader
Stephanie McGregor – BioBank Faculty Leader
William Rehrauer – TRIP Co-Faculty Leader
TSB - BioBank
The TSB BioBank, under our umbrella protocol, provides high-quality human tissues, blood and other biospecimens that are prospectively collected, processed, and stored for distribution to investigators, with or without their own IRB protocol, in accordance with procedures that comply with the confidentiality, safety and all other regulatory standards set by UW-Madison and the National Cancer Institute's Best Practices for Biospecimen Resources.
Facility Manager: Everlyne Nkadori
Biobank Lab Contact:
Phone: 608-262-8488 Hours: 7am-5pm M-F Email: biobank@uwcarbone.wisc.edu
TSB - TRIP Lab
The TSB Translational Research Initiatives in Pathology (TRIP) laboratory provides specialized histological, histochemical, molecular and imaging analyses and consultative services to support the individual research needs of investigators within the UW campus and beyond. Select services include the construction and distribution of tissue microarrays; routine histology and complex immunohistochemistry and in situ hybridization; multispectral fluorescent and bright field imaging with quantitative morphometric analysis via Vectra and Nuance instruments; cell line authentication, PCR and quantitative RT PCR analyses.
Facility Manager: Karla Esbona
Trip Lab Contact:
Phone: 608-265-9168 Hours: 6:30am-5pm M-F
Email: trip@pathology.wisc.edu
TSB - Experimental Animal Pathology Lab (EAPL)
The mission of the Experimental Animal Pathology Laboratory (EAPL) is to provide a comprehensive array of histopathology services and expertise that enable UWCCC members to fully exploit the power of animal models of human cancer to reveal mechanisms that contribute to cancer development, progression, and responsiveness to therapies. Contact Us at EPL@cancer.wisc.edu
Facility Manager: Joe Hardin
EAPL Lab Contact:
Phone: 608-262-1836 Hours: 8:00am-4:30pm M-F
Email: epl@cancer.wisc.edu