Biostatistics Shared Resource


The mission of the Biostatistics Shared Resource (BSR) is to promote excellence in cancer research at UW Carbone (UWCCC) by providing outstanding biostatistical support and collaboration to UWCCC members. Statistical consultation is especially valuable during the planning stage of a research study or a proposal for extramural funding. The early and continuing participation of a biostatistician always improves a grant proposal and the ensuing research. The collaboration of biostatisticians in the final analyses, resulting in abstracts for presentation and publications, greatly strengthens the credibility of the study findings to the cancer research community.

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Leadership

Faculty Leader

Hongyuan Cao, PhD

Facility Manager

Roxana Alexandridis, PhD

Using the Facility

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  • A basic level of consulting/collaborative support is provided free of charge to all peer-reviewed, cancer-related projects. Early stage interaction is especially encouraged.
    UWCCC members who require more extensive biostatistical support are expected to provide funding through individual grants, usually by including effort, salary and computing support for the biostatistician.
  • All consulting/collaborative support for non-peer-reviewed projects must be fully funded from appropriate funding source.
  • Requests for all services must come through the web portal request system. Under the ICTR membership question, it is not necessary to be an ICTR member to receive biostatistics support as a UWCCC member.
  • Requests for statistical collaboration on proposals for peer-review external funding must be received at least two months prior to submission.

Consulting on the planning and experimental design of studies

  • Advice on appropriate experimental design
  • Problem definition and statistical methodology
  • Definition of study endpoints
  • Sample size requirements
  • Definition of data items required
  • Determination of randomization and stratification

If necessary and for clinical and population-based studies:

  • Selection of study subjects and appropriate control groups
  • Recruitment strategies
  • Availability of data from related studies
  • Design of case report form

Assisting in the conduct of studies

  • Monitoring of studies
  • Data management or electronic transfer of data from other related studies
  • Development of systems for quality control, progress reports, and presentation of interim analyses

Analyzing completed studies

  • Determination of appropriate statistical methodology
  • Production of final study reports including graphs and tables or other summaries suitable for presentation and publication
  • Interpretation of statistical results, appropriate documentation and relevant literature

Any published research which received funding from the UWCCC Cancer Center Support Grant (CCSG), including the use of UWCCC Shared Resources to generate or analyze data or conduct clinical trials, must reference the UWCCC. See Acknowledging UWCCC in Publications, Posters and Presentations. Please acknowledge “UWCCC Biostatistics Shared Resource” for any work supported by the BSR.  Thank you!

Sample Acknowledgment

“The author(s) thank the University of Wisconsin Carbone Cancer Center Biostatistics Shared Resource, supported by P30 CA014520, for use of its services.”

Location

WARF 2nd Floor, 610 Walnut St., Madison, WI 53726