{"id":522,"date":"2017-04-12T18:45:05","date_gmt":"2017-04-12T18:45:05","guid":{"rendered":"https:\/\/cancer.wisc.edu\/research\/?page_id=522"},"modified":"2025-06-02T14:12:47","modified_gmt":"2025-06-02T19:12:47","slug":"scientific-accomplishments","status":"publish","type":"page","link":"https:\/\/cancer.wisc.edu\/research\/resources\/ddc\/smsf\/scientific-accomplishments\/","title":{"rendered":"Scientific Accomplishments"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"<p>Selected Scientific Accomplishments Computational Modeling and Docking Synthesis Screening siRNA Screening James Keck, PhD &#8211; Cell Signaling Program NIH R01 GM068061 CFAM (2-[2-chloro-5-(trifluoromethyl)anilino]-5-methoxybenzoic acid) identified in HTS at Small Molecule Screening Facility (SMSF) by disruption of protein interaction involved in genome maintenance. CFAM co-crystalized with target Exonuclease I (in black in Figure). In-silico docking of&hellip;<\/p>\n","protected":false},"author":61,"featured_media":0,"parent":98,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"class_list":["post-522","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/cancer.wisc.edu\/research\/wp-json\/wp\/v2\/pages\/522","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cancer.wisc.edu\/research\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/cancer.wisc.edu\/research\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/cancer.wisc.edu\/research\/wp-json\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/cancer.wisc.edu\/research\/wp-json\/wp\/v2\/comments?post=522"}],"version-history":[{"count":24,"href":"https:\/\/cancer.wisc.edu\/research\/wp-json\/wp\/v2\/pages\/522\/revisions"}],"predecessor-version":[{"id":33171,"href":"https:\/\/cancer.wisc.edu\/research\/wp-json\/wp\/v2\/pages\/522\/revisions\/33171"}],"up":[{"embeddable":true,"href":"https:\/\/cancer.wisc.edu\/research\/wp-json\/wp\/v2\/pages\/98"}],"wp:attachment":[{"href":"https:\/\/cancer.wisc.edu\/research\/wp-json\/wp\/v2\/media?parent=522"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}