SHOW’s selected scientific accomplishments include (1) Dr. Noelle LoConte’s research to survey past cancer survivors in the SHOW cohort which informed Wisconsin’s Comprehensive Cancer Control Plan for 2020-2030 on survivor health priorities, (2) Dr. Dudley Lamming’s examination of branched-chain amino acids from plasma samples from the SHOW biorepository and linking the analysis to existing data on the participants, and (3) Dr. Lisa Cadmus-Bertram was able to utilize the SHOW statewide infrastructure to launch a quantitative survey among rural women in the state. Read more below.
Noelle LoConte, MD – Informing Wisconsin’s Comprehensive Cancer Control Plan
Dr. LoConte and collaborators conducted a mail-based survey to past cancer survivors in the SHOW cohort (N=306). The findings from this study have informed Wisconsin’s Comprehensive Cancer Control Plan for 2020-2030 on survivor health priorities. The study has also contributed to publications on the financial toxicity of cancer and on alcohol use during chemotherapy.
Dudley Lamming, PhD – Linking Amino Acid Analysis to Participant Data
Dr. Lamming examined branched chain amino acids in 788 human plasma samples from the SHOW biorepository. He linked the amino acid analysis to existing nutrition, BMI and biosample data on the SHOW participants. This study found a similar relationship between isoleucine intake and metabolic health in both the mouse model and in the SHOW cohort.
Lisa Cadmus-Bertram, PhD, MPhil, MS – Awareness of Physical Activity Guidelines
Dr. Cadmus-Bertram was able to utilize the SHOW statewide infrastructure to conduct cost-effective focus groups in several rural communities around the state, design a questionnaire to identify barriers to physical activity and then launch a quantitative survey of over 350 rural women in under a year.
